产品货号:
Z38819
中文名称:
HSP47/SERPINH1抗体
英文名称:
Anti-HSP47/SERPINH1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HSP47/SERPINH1 Antibody |
指标别名 | 47kDa heat shock protein;AsTP3;CBP1;CBP2;Colligin;gp46;HSP47;PIG14;PPROM;RA A47;Serpin H1;SERPINH1;SERPINH2 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | SERPINH1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Hsp47 |
实际分子量 | 46KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Heat shock protein 47,also known as SERPINH1 or HSP47,is a serpin which serves as a human chaperone protein for collagen.This protein is a member of the serpin superfamily of serine proteinase inhibitors.Its expression is induced by heat shock.The protein localizes to the endoplasmic reticulum lumen and binds collagen;thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules.Autoantibodies to this protein have been found in patients with rheumatoid arthritis.It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and,when absent,the rate of transit from the ER to the Golgi is increased and the helical structure is compromised. |
Uniprot ID | P50454 |
基因名全称 | Serpin H1 |
推荐稀释比 | Western blot (WB) 1:400~800 Immunohistochemistry in paraffin section (IHC) 1:20~100 |
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